Personality phenotype has been associated with subsequent dementia in studies of older adults. This study used Project Talent data to examine whether personality during adolescence—a time when pre-clinical dementia pathology is unlikely to be present—confers risk for dementia in later life.

Project Talent is the largest, most comprehensive study of high school students ever conducted in the United States. Since its launch in 1960, researchers have continued to collect data on the original participants and now its data are helping AIR researchers study possible risk and protective factors of Alzheimer’s disease and related dementias. Project Talent Director and AIR Vice President Susan Lapham answered a few questions about the project, its history, and its potential influence.

New research finds that high school students’ personality traits may be linked to a heightened or lessened risk of death around 50 years later. These findings, published online in the Journal of Epidemiology & Community Health, come from an in-depth analysis of AIR’s Project Talent, now in its 59th year.

As the U.S. deals with the growing number of Americans living with Alzheimer's disease and related disorders, a new study suggests that those at risk of developing dementia in later life could be identified in adolescence, giving them the opportunity to receive interventions to offset the risk.