Oklahoma is among the states hardest hit by a combination of national trends in nonmedical uses of opioid prescription drugs, past-year heroin use, and opioid-related mortality. AIR recently led and evaluated a project for the Agency for Healthcare Research and Quality—Increasing Access to Medication-Assisted Treatment Among Rural Providers—to train rural Oklahoma primary care clinicians to identify and treat patients with opioid use disorders using medication-assisted treatment, an evidence-based intervention that combines behavioral therapy and medication to treat substance use disorders.